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Health

Pfizer (PFE) Q2 earnings report 2023

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Pfizer on Tuesday reported second-quarter adjusted earnings that topped Wall Street’s expectations, but posted revenue that fell short of estimates due to a plunge in Covid product sales.

Pfizer reported second-quarter sales of $12.73 billion, down 54% from the same period a year ago.

Here’s how Pfizer results compared with Wall Street expectations, based on a survey of analysts by Refinitiv:

  • Earnings per share: 67 cents per share adjusted, vs. 57 cents per share expected
  • Revenue: $12.73 billion, vs. $13.27 billion expected

The company’s Covid vaccine raked in $1.49 billion in sales, down 83% from the year-ago quarter. Pfizer’s Covid antiviral pill Paxlovid posted $143 million in revenue, a drop of 98%.

Together, the products pulled in $1.6 billion in revenue for the quarter. That compares with roughly $17 billion in sales during the same period a year ago.

“The contraction in revenues was driven by the anticipated decline in Paxlovid and Comirnaty sales,” Pfizer CFO David Denton said during an earnings call on Tuesday. 

Denton noted that Pfizer is prepared to cut costs if Covid product revenues for the full year are “less than what we assumed.” The company reaffirmed its forecast of $13.5 billion in Covid vaccine sales and $8 billion in revenue for Paxlovid for 2023.

He added that Pfizer would design the strategy to support its goal of growing its operating profit margin, and expects the effort to “begin to yield results in 2024.”

“We look forward to sharing specific details of this program in our upcoming earnings calls,” Denton said during the call.

Pfizer and rival drugmakers like Moderna have seen a steep drop in Covid-related sales this year as the world emerges from the pandemic and relies less on blockbuster vaccines and treatments that help protect against the virus.

Pfizer, Moderna and Novavax are preparing for the U.S. to shift Covid products to the commercial market, which means they will start selling vaccines and treatments directly to health-care providers this fall.

For the second quarter, Pfizer booked net income of $2.33 billion, or 41 cents per share. That fell from $9.91 billion, or $1.73 per share, during the same period a year ago. 

Excluding certain items, the company’s earnings per share were 67 cents per share for the quarter. 

Looking ahead, the New York-based company narrowed its 2023 sales forecast to $67 billion to $70 billion, from a previous forecast of $67 billion to $71 billion. 

Pfizer reiterated its full-year adjusted earnings outlook of $3.25 to $3.45 per share.

Pfizer CEO Albert Bourla said during an earnings call Tuesday that there is clearly a “higher level of uncertainty” about demand projections for Covid products than for the rest of the company’s business.

He noted that the second half of the year will “play a bigger role in informing our expectations for the long-term demand” of the company’s Covid vaccine and Paxlovid. Utilization “follows very closely” with Covid infection rates, he said.

“We expect a new COVID-19 wave to start in the U.S. this fall, and this expectation is supported by the increase in infection rates we are already seeing,” Bourla said, referring to a slight uptick in Covid cases reported to the Centers for Disease Control and Prevention over the last few weeks. 

Pfizer’s stock rose nearly 1% in early morning trading. The company’s shares have dropped nearly 30% this year, putting Pfizer’s market value at roughly $203 billion.

Pfizer’s non-Covid drugs

Excluding Covid products, drugs from recently acquired companies largely fueled revenue. 

Those sales include Biohaven Pharmaceuticals migraine drug Nurtec ODT and Global Blood Therapeutics’ sickle cell disease treatment Oxbryta, which drew in $247 million and $77 million, respectively.

The company said revenue was also driven by strong sales of Vyndaqel drugs, which are used to treat a certain type of cardiomyopathy, a disease of the heart muscle. Those drugs booked $782 million in sales, up 42% from the second quarter of 2022.

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Other drugs weighed on revenue, however. 

Inflectra, a monoclonal antibody used to treat a range of inflammatory autoimmune diseases, posted $74 million in sales. That total fell 46% from the same period a year ago. 

Pfizer’s Ibrance, which treats a certain type of breast cancer, posted $1.24 billion in sales, down 6% from a year ago. 

Pfizer looks to drug pipeline, M&A

Pfizer is in a transition period as it navigates its post-pandemic boom. The company is pinning its hopes on mergers and acquisitions and a record pipeline to pivot to new areas of growth. 

Bourla noted that the company is halfway to its goal of launching 19 new products or drug indications in an 18-month span – a target set last year. Indications refer to using a drug for a different disease type.

Pfizer had six product approvals and four launches in the first six months of the year. The company expects six more approvals and six launches during the second half of the year. 

Bourla said Pfizer expects revenue from this year’s new products to accumulate “largely in the second half of 2023 because the first-half launches occurred late in the second quarter.”

Pfizer’s upcoming launches include its updated Covid shot, which is designed to target the omicron subvariant XBB.1.5.

Bourla said the company expects to sell the Covid vaccine in the commercial market in September, assuming the Food and Drug Administration approves it and makes it available to the public by the end of August. 

Pfizer is also expected to roll out its vaccine for respiratory syncytial virus this fall. 

The FDA approved the shot in late May, and the Centers for Disease Control and Prevention recommended the jab to adults 60 and above. But the CDC says seniors should work with their health care providers to decide if taking a shot is right for them. 

Denton said that the guidance to consult with doctors first will likely “slow its uptake in the U.S.” 

Pfizer executives also provided updates on the company’s $43 billion acquisition of cancer therapy maker Seagen – a deal Pfizer believes could contribute more than $10 billion in risk-adjusted sales by 2030. 

Bourla said the company is working closely with regulators that are reviewing the deal, including the U.S. Federal Trade Commission and the European Commission, the European Union’s executive body.

The FTC asked Pfizer and Seagen for more information on their proposed merger during the second quarter. The move came as the agency cracks down on similar deals in the pharmaceutical industry. 

Categories
Science

One Easy Power Query Devastates ‘Internet-Zero’ Pipe Desires • Watts Up With That?

Originally posted in Western Journal

By Steve Goreham

Which is more environmentally friendly — an energy source that uses one unit of land to produce one unit of electricity, or a source that uses 100 units of land to produce one unit of electricity?

The answer should be obvious.

Nevertheless, “green” energy advocates call for a huge expansion of wind, solar and other renewables that use vast amounts of land to replace traditional power plants that use comparatively small amounts of land.

Vaclav Smil, professor emeritus at the University of Manitoba in Canada, extensively analyzed the power density of alternative sources used to generate electricity. He defined power density as the average flow of electricity generated per square meter of horizontal surface (land or sea area).

Estimating power density is complex. Smil included plant area, storage yards, mining sites, agricultural fields, pipelines and transportation, and other associated land and sea areas in his analysis.

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Smil’s work allows us to compare the energy density of electricity sources. If we set a nuclear plant to one unit of land required for one unit of electricity output, then a natural gas-powered plant requires about 0.8 units of land to produce one unit of output. A coal-fired plant uses about 1.4 units of land to deliver one unit of power.

But renewable sources require vastly more land. A standalone solar facility requires about 100 units of land to deliver the same average electricity output as a nuclear plant that uses one unit of land.

A wind facility uses about 35 units of land if only the concrete wind tower pads and service roads are counted, but over 800 units of land for the entire area spanned by a typical wind installation.

Production of electricity from biomass has the poorest energy density, requiring over 1,500 units of land to output one unit of electricity.

As a practical example, compare the Ivanpah Solar Electric Generating System in the eastern California desert to the Diablo Canyon Nuclear Plant near Avila Beach, California.

The Ivanpah facility produces about 793 gigawatt hours per year and covers an area of 3,500 acres. The Diablo Canyon facility generates about 16,165 gigawatt hours per year on a surface area of 750 acres. The nuclear plant delivers more than 20 times the average output on about one-fifth of the land, or 100 times the power density of the solar facility.

To approach even 50 percent renewable electricity using primarily wind and solar systems, the land requirements are gigantic.

“Net-Zero America,” a 2020 study published by Princeton University, calls for wind and solar to supply half of U.S. electricity by 2050, up from about 14 percent today. The study estimated that this expansion would require about 228,000 square miles of new land, not including the additional area needed for transmission lines.

That is larger than the combined area of Illinois, Indiana, Iowa, Kentucky, West Virginia and Wisconsin. This area would be more than 100 times as large as the physical footprint of the coal and natural gas power systems that would be replaced.

Taking land for wind and solar can seriously impact the environment.

Standalone solar systems blanket fields and deserts, blocking sunlight and driving out plants and animals. Since 2000, almost 16 million trees have been cut down in Scotland to make way for wind turbines, a total of more than 1,700 trees felled per day. This environmental devastation will increase the longer net-zero goals are pursued.

Wind and solar require vast amounts of land to generate the electricity required by modern society. Without fears about human-caused climate change, these systems would be considered environmentally damaging.

Net-zero plans for 2050, powered by wind and solar, will encounter obstacles with transmission, zoning, local opposition and just plain space that are probably impossible to overcome.

For more on energy and Net Zero, go to WUWT’s ClimateTV page.

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Categories
Entertainment

Serena Williams & Husband Be taught The Gender Of Their New Child

Continued congratulations are in order for Serena Williams and her husband, Alexis Ohanian, as the couple just learned the gender of their second child. As The Shade Room previously reported, the couple is expecting their second child and most recently embarked on a baby moon in June.

Williams initially revealed her pregnancy before attending the Met Gala in May.

RELATED: Bammin’ Babymoon! Serena Williams & Family Enjoy Vaycay Ahead Of Athlete’s Second Child

Serena Williams, Alexis Ohanian & Daughter Olympia Learn The New Baby’s Gender

Over the weekend, Williams took to her Instagram to alert fans that a video of her and Ohanian’s gender reveal would be published on YouTube. Additionally, Williams invited her Instagram followers to share what they believe is the gender of her and Ohanian’s second child.

“Big reveal coming soon to my YouTube channel. What do you think I’m having? Drop your guess below ⬇️ 💙💖”

On Monday, Williams returned to Instagram to inform her followers that the video finally went live.

“The big REVEAL is now live on YouTube! Did you guess right? 🔗 in bio.”

Once fans headed over to YouTube to watch the vlog, they were greeted by Williams, who shared that she “obviously is team pink but is nervous” because she didn’t have “any contingency plan” if the baby turned out to be a boy.

“I’m very excited. I’m a little nervous. I’m anxious, and Olympia is downstairs — she was ready to go an hour ago.”

As the family arrived at the gender reveal, they were greeted by various family members and friends, including William’s father and sister, Venus. However, as the gender reveal commenced, Ohanian decided to play a prank on Williams and Olympia.

The internet entrepreneur acted like the couple was doing a cake gender reveal. He proceeded to allow Williams and Ohanian to cut a slice. However, they were greeted by the yellow inside of the cake rather than a pink or blue inside.

“She’ll cut into this cake, probably be disappointed, and hopefully appreciate my troll,” Ohanian explained jokingly. “There’s a reveal after the reveal.”

When the real gender reveal commenced, Ohanian directed guests to look at the sky for a magnificent light show. Check out the moment below!

Williams & Ohanian’s Recent Babymoon

As The Shade Room previously reported, Williams, Ohanian, Olympia, and other family members embarked on a family babymoon in June. At the time, Williams shared photos of the getaway, remarking that Olympia couldn’t “stop posing.”

Ohanian and Williams initially revealed their pregnancy in May before arriving at the Met Gala, as reported by The Shade Room.

RELATED: Serena Williams’ Pregnancy, Red Carpet Roach &Kitty Couture: Five Unforgettable Met Gala 2023 Moments

Check out a video of Williams and Ohanian informing their daughter Olympia of the news below.