Week 2 of the NFL schedule begins on Thursday with an AFC East duel between the Buffalo Bills and the slight favorite Miami Dolphins and ends on Monday Night Football when Jalen Hurts and the Philadelphia Eagles play their first home and North American game against the Atlanta Falcons.
The Las Vegas Raiders entered the week as the biggest underdogs, having scored more than a touchdown in their road game against the Baltimore Ravens, while the Tampa Bay Buccaneers and Detroit Lions had the highest points totals in their Sunday afternoon game in Detroit. CJ Stroud and the Houston Texans gave up 6.5 points to Caleb Williams and the Chicago Bears in their Sunday night game.
Here's a look at all the games from week two. Football Power Index (FPI) by ESPN Sports Analytics. Odds current at time of publication. For the latest odds, visit ESPN BET.
Spreads, moneyline and totals for week 2 of the 2024 NFL
Buffalo Bills vs Miami Dolphins -2.5
Thursday, 8:15 p.m. ET, Prime Video
Money line: Bills (+120); Dolphins (-140)
In total: 48.5; Open: 50.5
FPI favorite: Bills by 0.4
San Francisco 49ers -5.5 against Minnesota Vikings
Sunday, 1:00 p.m. ET, CBS
Money line: 49ers (-250); Vikings (+210)
In total: 45.5; Open: 46.5
FPI favorite: 49ers with 5
Los Angeles Chargers -6 against Carolina Panthers
Sunday, 1:00 p.m. ET, CBS
Line movement: opened chargers -3
Money line: Chargers (-270); Panthers (+220)
In total: 39.5; Open: 42
FPI favorite: Chargers from 6.8
Indianapolis Colts -3 vs. Green Bay Packers
Sunday, 1:00 p.m. ET, FOX
Money line: Colts (-150); Packers (+130)
In total: 40.5; Open: 47.5
FPI favorite: Colts with 1.7
New York Giants vs. Washington Commanders -1.5
Sunday, 1:00 p.m. ET, FOX
Money line: Giants (+105); Commanders (-125)
In total: 43.5; Open: 42.5
FPI favorite: Commanders of 4.3
New Orleans Saints vs. Dallas Cowboys -6
Sunday, 1:00 p.m. ET, FOX
Money line: Saints (+220); Cowboys (-270)
In total: 46.5; Open: 44.5
FPI favorite: Cowboys of 4
Cleveland Browns vs Jacksonville Jaguars -3
Sunday, 1:00 p.m. ET, CBS
Money line: Browns (+130); Jaguars (-150)
In total: 41.5; Open: 44.5
FPI favorite: Jaguars with 2.8
New York Jets -3.5 against Tennessee Titans
Sunday, 1:00 p.m. ET, CBS
Money line: Jets (-185); Titans (+155)
In total: 40.5; Open: 44
FPI favorite: Jets by 2.9
Tampa Bay Buccaneers vs Detroit Lions -7.5
Sunday, 1:00 p.m. ET, FOX
Money line: Buccaneers (+290); Lions (-360)
In total: 51.5; Open: 48.5
FPI favorite: Lions with 6.1
Las Vegas Raiders vs Baltimore Ravens -9
Sunday, 1:00 p.m. ET, CBS
Money line: Robbers (+360); Ravens (-450)
In total: 41.5; Open: 44
FPI favorite: Ravens with 9.2
Seattle Seahawks -3.5 vs. New England Patriots
Sunday, 1:00 p.m. ET, FOX
Money line: Seahawks (-190); Patriots (+160)
In total: 38.5; Open: 42.5
FPI favorite: Seahawks with 2.3
Los Angeles Rams vs Arizona Cardinals -1
Sunday, 4:05 p.m. ET, FOX
Money line: Rams (+EVEN); Cardinals (-120)
In total: 47.5; Open: 47.5
FPI favorite: Rams by 1.4
Cincinnati Bengals vs. Kansas City Chiefs -5.5
Sunday, 4:25 p.m. ET, CBS
Line movement: opened Chiefs -3.5
Money line: Bengals (+195); Chiefs (-230)
In total: 47.5; Open: 48.5
FPI favorite: Chiefs with 6.2
Pittsburgh Steelers -2.5 against Denver Broncos
Sunday, 4:25 p.m. ET, CBS
Line movement: opened Broncos -0.5
Money line: Steelers (-140); Broncos (+120)
In total: 36.5; Open: 40.5
FPI favorite: Steelers with 3
Chicago Bears vs Houston Texans -6
Sunday, 8:20 p.m. ET, NBC, Peacock
Money line: Bears (+220); Texans (-270)
In total: 45.5; Open: 46.5
FPI favorite: Texans with 5.8
Atlanta Falcons vs Philadelphia Eagles -6.5
Monday, 8:15 p.m. ET, ESPN
Line movement: opened Eagles -4
Money line: Falcons (+230); Eagles (-280)
In total: 47.5; Open: 48.5
FPI favorite: Eagles with 5.5
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