Categories
Technology

Swiss Startup says that his AI climate forecast is defeated by Microsoft, Google

The Swiss Startup Jua has launched an AI-driven weather forecast button, which is that striking models of tech giants are beating, which may make the world's most accurate weather forecast system.

Jua claims that his model-called EPT-2-SEI faster and more precisely than both Aurora from Microsoft and the Google Deepmind Graphcast. In separate, examined by experts StudiesIt was shown that both models are more precise than the European Center for Middle Weather forecasts (ECMWF) of the ESE forecast with a medium area, which is widely considered worldwide.

Jua supports his bold demands with a new report that was published today and sets with top animal models, including Aurora and two of the best ECMWs, from EPT-2 from Head-to Head: EnS and IFS-Gres.

According to the newspaper, EPT-2 came out and provided the most precise forecasts across the board. Aurora hit important variables such as 10 meters wind speed and 2-meter air temperature over a period of 10 days, predicted 25% faster and recorded the lowest error values of all tested models. Jua says that this has achieved all of this, while she used 75% less computing power than Aurora, the second most efficient system was tested.

According to Jua, research is to be published in the open access archivariv-arxiv in the next week.

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The Graphcast model from Deepmind was not included in the study. Nevertheless, Marvin Gabler, CEO and co -founder of Jua, is confident that it can surpass the entire competition.

“We respect players like Microsoft Aurora, Graphcast and tomorrow.

The AI-based weather forecast has led waves in recent years, which are due to the demand for more precise and cheaper opportunities to predict the climate of the earth.

Traditional weather models, such as those of ECMWF or NOAA, use complex physics equations that are operated on billions in dollars supercomputers. AI models skip the equations, learning patterns from massive data records, which makes thousands of forecasts faster on much cheaper, less energy-intensive machines.

According to Gabler, however, Jua goes one step further than previous AI-based forecast. “While other AI retrofit in Legacy systems, we have built up a native physics simulation that understands how the atmosphere of the earth actually behaves,” he said.

Jua released his first global AI weather model three years ago. The startup has now introduced a total of $ 27 million of supporters from supporters, including 468 capital, future energy ventures and promus ventures.

Categories
Science

ICJ guidelines are obliged to alleviate CO2 emissions.

Eric Worrall essay

“States … have additional commitments to take the lead in combating climate change by restricting their greenhouse gas emissions …”

The press release;

If someone has the patience, the full 133 -side judgment (mainly in English) is available here (backup copy here).

From the advisory opinion press release + judgment;

In the climate change contracts, binding obligations for the states were determined to ensure the protection of the climate system and other environmental parts from anthropogenic greenhouse gas emissions. These obligations include the following:

(A) States parties of the United Nations' framework agreement on climate change are obliged to take measures to contribute to reducing greenhouse gas emissions and adapt to climate change.

(b) States parties that are listed in Appendix I to the united nations' framework agreements on climate change have additional obligations to take the lead in combating climate change by restricting their greenhouse gas emissions and improving their greenhouse alleys and reservoirs.

(c) States parties to the United Nations Convention on Climate Change are obliged to work together in order to achieve the underlying goal of the convention; (d) States of the Kyoto protocol must comply with the applicable provisions of the protocol.

(e) States parties to the Paris Agreement are obliged to act with duties in accordance with their common but differentiated responsibilities and respective skills that are able to achieve an appropriate contribution to achieving the temperature goal specified in the agreement;

(f) States parties of the Paris Agreement are obliged to prepare, communicate and maintain consecutive and progressive national articles, which, among other things, can achieve the temperature goal of limiting global warming to 1.5 Ieltes pre-industrial level.

(g) States parties of the Paris Agreement are obliged to pursue measures that are able to achieve the objectives defined nationwide in their consecutive nationwide. And

(h) The states of the Paris Agreement have obligations to adapt and collaboration, including technology and financial transfers, which must be carried out in good faith.

– The usual international law gives obligations for states to ensure the protection of the climate system and other environmental parts from anthropogenic greenhouse gas emissions. These obligations include the following:

(A) States have the obligation to prevent the environment considerable damage By acting with duty of care and to prevent activities that are carried out in their responsibility or control, prevent the climate mode and other environmental parts in accordance with their common but differentiated responsibilities and respective skills.

(B) States have the obligation to work together in good faith in order to significantly harm the climate mode and other environmental partsWhich requires sustainable and continuous forms of cooperation by states if they take measures to prevent such damage.

Read more: the same link as above

Despite the court who claims that the judgment is a consultation, the body of the judgment seems to say that all members of the UN, including the United States, are obliged to respect this ICJ judgment according to the UN Charter, since the United States has not necessarily used.

b) Mandatory for cooperation to protect the environment 140. The obligation to cooperate is at the core of the United Nations Charter. Article 1 of the Charter Commits States ”[t]o Got the international cooperation in solving international problems of an economic, social, cultural or humanitarian character. This obligation was presented in the basic “explanation of the principles of international law in relation to friendly relationships and cooperation between states in accordance with the Charter of the United Nations (Resolution 2625 (XXV) of the General Assembly) of October 24, 1970) (hereinafter referred to as“ explanation on friendly relationships). The Court has found that “the assumption by states of this text provides an indication of its statement on the usual international law (military and paramilitary activities in and against Nicaragua (Nicaragua against United States of America), merit, judgment, ICJ, 1986, p. 101, para. 191). This observation also applies to the obligation to capture expression in many binding and non-binding instruments in many binding and non-binding instruments that refer specifically to the environment. The obligation to cooperate is a central obligation according to the climate change contracts and other environmental contracts explained below (see paragraphs 214-218 and 260-267). Other examples include the principle 24 of the Stockholm Declaration and the principle 7 of the Rio declaration for the environment and development (hereinafter referred to as the “Rio Declaration”), which recognize cooperation as an essential element for the protection of the environment. In view of the related state practice, The court assumes that the obligation of the states to work together to protect the environment (See climate change, advisory opinion, ITLos reports 2024, p. 110, para. 296; MOX plans (Ireland against Great Britain), preliminary measures, order of 3 December 2001, Itloslos report 2001, p. 110, para. 82).

Read more: https://www.icj-cij.org/sites/default/files/case-related/187-20250723-adv-01-00-en.pdf

I am not a right -wing expert, but the argument that the habitual right in terms of international relationships has weight seems to be weak, but not necessarily weak enough to have released it immediately without much time and money.

The US Senate ratified the UN Charter in 1945, although the UN has now granted powers that were not part of the original charter. I do not remember that the Senate has ever ratified the US's alleged climate obligations as part of this Charter from 1945. The claim that the United States has a climate obligation as part of a charter ratified by the US Senate long before the UN has been involved in the climate game seems to be a route.

The argument of “common character” may be that states have compliance with compliance, an indication of the approval of earlier US administrations for non -crowned and expansion of authority. If this is correct, the ICJ Council would make an assertion that the United States should keep the flap and do what is said to them.

Obviously, this ICJ judgment of NGOs and governors who do not agree with the climate policy of President Trump offers a lot of scope for mischief. I can see how this ICJ judgment makes many lawyers rich.

Interestingly, there has recently been an increase in lithium prices, around $ 8.50 / pound at the end of June around 10 US dollars per pound. The explanations that I have read claims that this is due to a global deletion of the excess inventory as speculation that the ICJ decision could possibly increase.

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Categories
Entertainment

Kelly Osbourne Closing Ozzy Osbourne Video earlier than demise

The children of Ozzy Osbourne, Jessica and Louis Osbourne honor their father after his death

Ozzy Osbourne Could change, but luckily he had his daughter at his side.

Days before the Black Sabbath Frontmann died after a long fight against Parkinson's disease. Kelly Osbourne Looked a look into a sweet moment with her father.

Indeed that Osbournes Alum posted a video on her Instagram stories on July 20 at the dining table with Ozzy, via TMZ. When she shows her and Sid Wilson2-year-old son SidneyShe says: “Good morning!”

The youngest daughter of Ozzy and Sharon Osbourne Duty to her father and tells him: “Dada, say good morning!” The “Iron Man” singer who attracts a black T -shirt and headphones answers enthusiastically: “Good morning!”

The clip, which seems to be the last public video of the singer, was shared two days before the Osbourne family – including his children Kelly. Aimee OsbournePresent Jack OsbournePresent Louis Osbourne And Jessica Osbourne—Conbonted ozzy's death.

Categories
Sport

Anatomy of an NFL holdout: What it is like for gamers, brokers, groups

  • John KeimJul 23, 2025, 06:00 AM ET

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      John Keim covers the Washington Commanders for ESPN. He joined ESPN in 2013 after a stint with the Washington Post. He started covering the team in 1994 for the Journal Newspapers and later for the Washington Examiner. He has authored/co-authored four books. You can also listen to him on ‘The John Keim Report’, which airs on ESPN Richmond radio.

Future Hall of Fame offensive tackle Walter Jones spotted something in a newspaper that changed everything about his monthslong holdout in 2002.

Jones was trying to secure a long-term deal from the Seattle Seahawks. After holding out of all team activities for the entirety of training camp, he extended his absence into the first two games of the regular season.

But, while leafing through a newspaper at his Huntsville, Alabama, home, Jones read something that compelled him to sign a deal that same day:

The amount of money he had forfeited.

Players receive their paychecks on a weekly basis during the season. So missing Weeks 1 and 2 meant two checks totaling $578,823 had not been deposited into Jones’ bank account. So he signed the franchise tag tender that had been awaiting him for $4.92 million.

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“[The article] was like, ‘This is how much money Walter [is] losing,'” Jones said. “I was like, ‘Wait, I don’t want to lose any money.’ So I went in.”

It is a harsh reality of holding out — a process in which a player does not report to training camp, despite being under contract, and becomes subject to mandatory fines. The emotional twists and turns for all involved in a holdout — or hold-in (when a player attends team activities to avoid being fined but doesn’t participate ) — are many. Players must deal with uncertainty over their future and missing time with teammates. General managers know they must get an important player signed while facing pressure from fans, owners and coaches. Agents not only negotiate deals but also handle the players’ emotions. And through it all, coaches are left to twist in the wind, wondering when one of their best players will be available to the team on the field, if at all.

“Holdouts are brutal, man,” said longtime agent Vince Taylor, who has had two clients hold out on three occasions, including twice with San Francisco 49ers left tackle Trent Williams. “I’ll say this for an agent or a player who has never experienced it, I don’t think you can tell them enough how brutal it is.

“Don’t push that button unless you really [plan to] go all the way.”

As NFL training camps opened this week, there were two high-profile veteran holdouts: Cincinnati Bengals defensive end Trey Hendrickson and Washington Commanders wide receiver Terry McLaurin. Both players have one year left on their current contracts.

Holdouts come at a hefty cost. Players are fined $50,000 for each day they hold out. Previously, teams could waive those fines. But that loophole was closed under the current collective bargaining agreement ratified in March 2020. Now, only players on rookie contracts can get that relief.

“It’s a toothache,” former NFL general manager Bill Polian said. “It’s there all the time.”

Here are stories of notable NFL holdouts from the perspectives of a coach, agent, general manager and player.

The coach

Jay Gruden says coaches are often left powerless when a star player holds out. Jonathan Newton/Getty Images

Washington head coach Jay Gruden felt helpless in the summer entering the 2019 season. His job was in jeopardy and his team was coming off an injury-induced collapse that ended in a disappointing 8-9 record and a second straight campaign without a playoff berth. The starting quarterback they hoped to build around for the next several years, Alex Smith, was recovering from a horrific broken leg suffered against the Houston Texans in November — a setback that underscored the rash of injuries, particularly on defense, that Gruden & Co. were faced with entering a fraught 2019.

Making matters even more difficult: Their best offensive player, left tackle Trent Williams, was holding out.

Williams, who had been selected to his seventh straight Pro Bowl the previous year, was upset by how Washington handled things after he was diagnosed with a rare form of skin cancer. He also had no guaranteed money left on his deal.

That left Gruden and his staff to deal with what was left of the on-field product. Not least of which was replacing Williams, entering his age 31 season and squarely in the prime of a likely Hall of Fame career, with 36-year old Donald Penn, a solid NFL veteran, but one whose career wouldn’t last past that 2019 season.

“It’s difficult because you count on your best players to play,” Gruden said. “It helps you in your ability to win football games, especially when you go from maybe the best starting tackle of all time to a guy who’s on the tail end of his career. You just try to limit the damage and make sure you take care of your best guys.

“Unfortunately for the coach, it’s really out of your hands.”

The coach knows he needs the player, but the mindset becomes similar to when a player gets hurt — the coach just has to adapt to who’s available. However, there are some crucial differences.

“The holdouts are a little different than injuries,” Gruden said. “You feel like you can control the holdout, just pay the guy. S— we need him. I understand there’s a salary cap and all that, but the one thing you want to do is make sure you take care of the guys that are your best players. It’s just hard to replace guys that are top of the food chain. Receivers that put points on the board and left tackles to protect the quarterback’s blind side and quarterbacks and pass rushers, those are ones you got to try to keep.”

Adding to any coach’s dilemma in these situations, Gruden said a coach can’t interfere in the contract proceedings, unless they also serve as a general manager. Before Williams’ decision to hold out, Gruden had often let his star know how wanted and appreciated he was by him and his staff. During the holdout, the coach avoided all contact.

“That’s where you have to be careful as a coach,” Gruden said. “You can’t pit the player against the organization and take the player’s side. I’m just going to stay in my lane and coach the football team. And that’s kind of what I did. That’s why I stayed away from texting and calling, ‘Hey man, I love you. I want you to come here, man, these guys are a–holes. They won’t pay.’ Then all of a sudden that gets back to you, so now you have division.”

Williams never played for Washington again, choosing to extend his holdout for the entirety of the 2019 season. He was traded to the San Francisco 49ers the following April.

Without Williams, Smith and a healthy defense, Gruden’s team sputtered to an 0-5 start. Gruden was replaced by then-assistant head coach and offensive line chief Bill Callahan before Game No. 6. Washington finished the season 3-13.

In the end, Gruden said Williams’ holdout didn’t make or break the season. But he learned firsthand how little power coaches possess during the process. And, though he said they might have won one game had Williams reported, Williams’ absence plus injuries to other players added up.

“It’s like, ‘Holy s—,'” Gruden said. “It was pretty frustrating. You just feel like the world, the football gods were against you.”

The agent

Trent Williams has staged two separate holdouts in his career — in Washington and San Francisco. Michael Zagaris/Getty Images

When Williams held out from Washington in 2019, his longtime agent, Vince Taylor, said he allowed for his client’s emotion to be heard. Williams felt the team didn’t handle his cancer scare well and that impacted his thoughts on a new contract with the team. But Taylor said he had another job to do as well.

“I had to slowly get him to a business mindset,” Taylor said. “And if you want to continue your career, these are the things we’re going to have to consider. It’s advantageous for us to get a business mindset and get the personal [concerns] to the side. In his mind he wasn’t [going to report]. He didn’t even want to stomach the fact that he had to be there.”

But for Taylor or any agent navigating a holdout, it’s not enough to negotiate a deal. And, he said, having gone through it now twice with Williams — and once with offensive tackle Jason Peters in 2008 with Buffalo — he’s better equipped to handle it. In 2019, Williams never reached an agreement with Washington and was traded in the offseason. Five years later, during a holdout with San Francisco, Williams received a $27.6 million salary and $48 million fully guaranteed, which his agency said was a record for non-quarterbacks over 30 years old.

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“The second time around, what it helps you with is the management of family, friends, wife, kids, media and things of that nature,” Taylor said.

Taylor said he’ll talk to or meet with a handful of people in the player’s “circle of trust.” He’ll lay out the possible scenarios — if it takes all summer; if it lasts into the season. With the player, he’ll lay out what to expect — like how much the player stands to be fined — while also making sure the player is maintaining his conditioning.

“You’re an agent, you’re a counselor, you’re a therapist, you’re a police officer, sometimes security guard, trying to keep the guy from going on a rant on social media,” longtime agent Damarius Bilbo said about navigating a holdout. “I mean, you’ve got to wear all those hats. The No. 1 thing is emotion.”

Bilbo was involved in running back Melvin Gordon’s holdout from the Los Angeles Chargers in 2019 and has had other players with contract issues, such as former Miami receiver Jarvis Landry and New Orleans running back Alvin Kamara. Bilbo said the word they used often was “value.” When they don’t feel valued, it fuels their emotions.

“For a guy to put his heart, soul and everything into his business, how do you tell a guy not to be emotional?” Bilbo said. “But when people are offering their opinion by way of social media, by way of podcasts and stuff, these players listen and it takes them. You never know what that trigger is going to be.

“It’s a constant [battle]. They don’t listen. And I get it. I get it. This is hard. It’s hard.”

Landry wanted an extension from Miami in 2017 but did participate in camp. However, for those who want to hold in — report to camp to avoid fines, but not fully participate in practice — it’s not always easy.

“There have been instances where coaches are pulling guys to the side and saying, ‘Hey, your agent, your representation is being difficult. We’re trying to get this done,'” Bilbo said. “They’re trying to talk him into believing that this is his market. Sometimes being in a building could be more of a distraction because obviously the media wants to talk to the guy. He’s not practicing, he’s on the sideline. I dealt with this last year with Matt Judon that led to him getting traded to the Falcons.”

Taylor said holdouts also can lead to other situations.

“That’s a prime time for agents to poach, too,” Taylor said. “Agents and friends of agents. There was one agent in Trent’s DMs, but luckily [our] relationship is strong.”

Ultimately, in a league where careers are typically shorter than other major sports, and where most players can be replaced, there’s something Bilbo doesn’t forget.

“The balance of power,” Bilbo said, “is always in favor of the organization.”

The GM

Former general manager Bill Polian served in the role for Buffalo, Carolina and Indianapolis. AP Photo/Paul Spinelli

Bill Polian recalled a nickname former GM Ernie Accorsi had for general managers enduring a holdout situation:

The fellow sufferers club.

In some ways, when one general manager goes through it they all do.

“You took so many slings and arrows publicly,” said Polian, who served in the role for Buffalo, Carolina and Indianapolis and was later an NFL analyst for ESPN. “Guys will call up and say, ‘Hey, I really empathize with you. This is terrible.’ Other people will offer advice: ‘Hey, don’t cave on this one. This is really important.’ On occasion, [NFL] management council will step in.

“I made those calls to guys that were in predicaments, too, to try and just provide a little positive reinforcement.”

The general manager becomes a lightning rod during these situations — fans upset that the team hasn’t signed a player; an agent whose client wants the deal done now; an owner that might not fully grasp the situation.

“If ownership is inexperienced or new, has been outside football,” Polian said, “then it’s a little more difficult because you have to explain the dynamics. And the agent is certainly playing a waiting game and using a public relations campaign against you, and you have to explain that if they’re new to it.”

ESPN analyst and former general manager Mike Tannenbaum, who dealt with holdouts as a general manager in Miami (Landry) and the New York Jets (cornerback Darrelle Revis), said he tried to remove the emotion from the negotiations. He also said a GM should not talk to the player, adding that he viewed himself as the agent for the team, and as such, he dealt only with the player’s agent.

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“It’s keeping alignment and knowing that there’s going to be tension points throughout the process until you get to where you want to go,” he said. “Just stick to the facts, look at the market, let the data drive us to where we want to go.”

Polian dealt with two holdouts as the GM in Carolina from 1995 to 1997: rookie running back Tim Biakabutuka and veteran edge rusher Kevin Greene. Both were difficult.

Polian said he never understood why Biakabutuka was holding out and that there wasn’t much dialogue with his agents. At then-owner Jerry Richardson’s urging, Polian “wrote them two rather strong letters, which I would almost never do in a holdout situation.”

They didn’t respond to that either.

Ultimately, the former Michigan star, whom the Panthers selected No. 8 in 1996, signed when various base salary escalators were agreed upon, after missing the first 27 days of training camp.

“They just capitulated on the eve of the season,” Polian said. “I don’t know what it was all about in the first place. To this day I don’t know what their aim was.”

In 1996, Greene signed a two-year deal with Carolina and, that season, was named first-team All-Pro after leading the league with 14.5 sacks. But he and his agents felt he had outplayed his two-year, $2 million contract. So, he held out.

Given Greene’s importance to a team that, in Year 2 of its existence, came one win from reaching the Super Bowl, Polian said his job was to keep coach Dom Capers informed of the proceedings on a weekly basis. When it became clear the matter was far from being resolved, he held a meeting with the personnel department and Capers.

“Start looking for a replacement,” he told the group. “This could go south.”

Which it eventually did. After the two sides failed to reach an agreement, Carolina cut Greene, who then signed with San Francisco.

Looking back, Polian said that parting ways with Greene was the cost of doing business as an NFL GM.

“You hope for the best, but you always have to prepare for the worst,” Polian said. “That’s what we did and that’s the GM’s job.”

The player

Walter Jones made a habit of holding out from 2002 to 2004. He finally got his long-term deal in February 2005. Otto Greule Jr/Getty Images

For three years, Walter Jones heard the same jokes from his Seattle teammates.

“Guys would make fun of me, like, ‘Hey, Walt, you remember when that happened in training camp? Oh, you wasn’t there!'” Jones said.

Technically, Jones said, he was never a holdout. He just never signed his franchise tag tender until finally reporting. But he certainly knew how to play the holdout game once he stopped costing himself game checks, and his game on the field never suffered.

Jones skipped training camp from 2002 to 2004 because of his contract; he made the Pro Bowl after each of those seasons. He credits that to workouts in Alabama with his high school coach. He’d run sprints, lift weights and push his Escalade back and forth in 20-yard intervals.

“My first year [holding out] was kind of hectic because you just didn’t know whether I was going to be ready because you’re doing all the workouts by yourself,” Jones said, adding he knew the importance of staying in shape.

“If I would’ve came in there out of shape, they would’ve said, ‘See this is why he needs to get to training camp,'” Jones, who maintained in lockstep with agents Roosevelt Barnes and Eugene Parker over what he wanted, said. “I always wanted to prove to them that even though I’m not here, I’m ready to play. … I don’t know if it made me a better player. I think I played longer by missing training camp.”

In 2014, tight end Vernon Davis skipped San Francisco’s mandatory minicamp while seeking an extension with two years left on his deal. That experience taught him a lesson: Missing time stinks. He received daily updates from his agent Todd France but didn’t want to hold out.

“It was frustrating. I was antsy,” Davis said. “I felt like I needed to smoke a cigarette sometimes. I didn’t do that, but I felt like I wanted to. … And it was just one of those things that just because you feel like you’re missing something, you feel like you’re behind.”

But for Jones, who rode his string of holdouts to eventually sign a seven-year, $52.5 million deal in February 2005, what he really missed were those first two game checks. He came from a small rural town and said the money he forfeited had staggered him. So he told his agents from that point on: No matter what, when payroll starts, he’s signing — jokes from teammates be damned.

“It was never something where guys resent you because you held out to try to get the money that you deserve,” he said. “Listen, man, you know this rising tide lifts all boats, right? So if you get more, someone else is going to get more.”

Categories
Health

Researchers strategy a common most cancers vaccine

Wild pixels | IStock | Getty pictures

A version of this article was first published in CNBCS Healthy Return's newsletter, in which the latest health news leads directly to their inbox. Subscribe here to get future expenses.

A universal cancer vaccine – what once seemed like a pipe dream – could approach reality.

On Friday, researchers from the University of Florida said that results from a new study could lead to the development of a universal shot that can start the immune system to combat cancer. The study of mice published in Nature Biomedical Engineering showed that an experimental MRNA vaccine increased the tumor control effects of a common cancer medication called Immun-Checkpoint inhibitors.

The vaccine is not designed for a certain virus or cancer cells, but to “wake up” the immune system against the disease “to react as if you are fighting a virus,” said a UF release.

“We found that a vaccine is used not to specifically target cancer, but to stimulate a strong immunological reaction, we were able to create a very strong reaction against cancer reaction,” said Dr. Duane Mitchell, co-author of the study and professor of neurosurgery at the medical college of Medicine at the university.

This is different from current approaches to cancer vaccines in which a goal is found that is expressed by many cancer patients or in the event of a case of Modern And MerchantDevelopment of personalized vaccines that are tailored to the specific tumor of each patient.

The universal vaccine has the potential to be used largely in cancer patients, “even a cancer-suffering cancer vaccine,” said Mitchell.

The UF researchers are still working on replicating the results in humans. If this is the case, a vaccine with a sizes could offer an alternative to operations, radiation and chemotherapy.

This is how the vaccine works: The MRNA shot essentially calls on the body to produce certain proteins that stimulate the immune system, including one that is called PD-L1 and can often be found on the surface or within cancer cells. These cells often use PD-L1 to hide from immune attacks.

By increasing PD-L1, however, the vaccine tumors can make more susceptible to immune checkpoint inhibitors that block this protein more susceptible and contribute to recognizing and destroying the immune system.

The study showed promising results on treatment-resistant tumors in skin cancer by combining the mrNA vaccine with a monoclonal antibody, a frequent immunotherapy medication that tries to draw the immune system aware that a tumor is foreign and attacked.

It also showed positive results when they were tested as a solo treatment of cancer of mouse, bones and brain test. In some cases, the tumors were completely eliminated.

“This paper describes a very unexpected and exciting observation: even a vaccine that is not specifically for a certain tumor or virus it is a mRNA vaccine-could lead to tumor-specific effects,” said the high-ranking author Dr. Elias Sayour, a pediatric oncologist from UF, in a release.

Feel free to send Annikakim.constantino@nbcuni.com tips, suggestions, ideas and data to Annika.

Latest in the healthcare system Tech: Digital Health Earning season is approaching.

We are only removed from the highlight of the digital health earnings season for a few days, and this quarter will certainly be interesting.

The two companies, the beginning of this year, went to the stock exchange, will report results for the first time since their debut. And since President Donald Trump's tax and expenditure law adopts and approaches his tariff period on August 1st, we will get an insight into the operation of digital health companies against a volatile macroeconomic and political backdrop.

Here are some of the reports on which CNBC will be observed:

Health hinge – August 5th

  • The digital physiotherapy company HEALTH will publish its result in the second quarter on August 5, its first report since its debut at the New York Stock Exchange in May. The stocks of Hinge were opened on May 229.25 and they act on Wednesday after trading with Intraday over $ 46. In his first quarter of this year this year rose by 50% to $ 123.8 million, compared to $ 82.7 million in the previous year, and this net income for the period was $ 17.1 million compared to a loss of $ 26.5 million before the previous year.

Omada Health – August 7th

  • The Virtual Chronic Care Company, Omada Health, will report results in the second quarter on August 7, which reveals finance data for the first time since his debut in June. The stocks of Omada were opened on June 6th at 23 USD and they act on Wednesday for trade in trade with around 19 US dollars. According to the prospectus, Omada's turnover rose by 57% in the first quarter to $ 55 million compared to $ 35.1 million in the previous year.

Hims & Hers Health – August 4th

  • Telemealth Company HIMS & HERS Health Reports Reports in the second quarter on August 4th and managers will probably have questions about his short -lived cooperation with jobs Novo Nordisk. In April, Novo Nordisk said that Wegovy would offer several telemedicine companies, including HIMS & Her, to expand access to the injection of the blockbuster weight loss. But at the end of June, the deal collapsed over the sale and promotion of cheaper qualifications from HIMS & Huls. The shares of HIMS & HIS rose by more than 100% after the intraday trade on Wednesday after the intraday trade.

Doximity – August 7th

  • Doximity, a digital platform for medical professionals, was one of the few breakout stars from 2024 when the company's share price more than doubled. Investors will observe closely whether the company can maintain its dynamics if the results report on August 7 in the first quarter of 2026. The stocks of doximity rose by more than 13% this year after the intraday trade on Wednesday.

Teladoc Health – July 29th

  • The CEO of Teladoc Health, Chuck Divita, has worked after four right quarters with sales declines and an extended slump in stock burglary to turn the once high -flying company in a row. The company will publish results in the second quarter on July 29. The TELADOC shares decreased by more than 4% by the time of Intraday trading on Wednesday.

We will have a lot to dive in the coming weeks. So keep the reporting of CNBC step.

Feel free to send tips, suggestions, story ideas and data to Ashley at Ashley.capoot@nbcuni.com.

Categories
Science

Chilly climate alloy opens up new alternatives for house know-how

A team of scientists has developed a new material that could change the construction of devices for space missions and other extremely cold environments. This new copper base retains its unique properties of the “form memory” even at temperatures such as -200 ° C.

Form memory alloys are fascinating materials that act like mechanical memory foam. When they are cold, they can be bent and twisted into different shapes. But if they are heated, remember their original shape and automatically snap back on it. This remarkable property makes it incredibly useful to create actuators that convert energy in machines in motion.

An example of the old school for an actuator that converts energy in motion within a DVD drive with lead screw and stepper engine. (Credit: Baran Ivo)

A good way to think about this concept is to imagine a thermostat in your house, which automatically adapts to the temperature or the mechanisms in space vehicles that have to move and adapt without human intervention. These applications are based on materials that can predictably react to temperature changes.

So far, form memory has been a major restriction in extreme cold. The most common type made from nickel and titanium stops working properly below -20 ° C. Some could work below -100 ° C at temperatures, but they were not practical for applications in the real world.

This created a real challenge for space technology, in which the devices are regularly exposed to temperatures far below -100 ° C. Space telescopes, satellites and other instruments need reliable moving parts that can work in the rough cold of the room.

Artist's impression of the James Webb World space telescope, which works as cold as -223 ° C at temperatures (loan: NASA)

The research team from several Japanese institutions, including Tohoku University and the Japan Aerospace Exploration Agency (JAXA), has developed the new copper-aluminum-manner alloy, which maintains its shape memory properties at extremely low temperatures. They successfully tested their alloy at -170 ° C, which showed that they could effectively control the heat transfer by switching between contact and non -contact states. This is great progress in materials science.

“We were very happy when we saw that it worked at -170 ° C, other form memory alloys simply can't do that” – Toshihiro Omori from the University of Tohoku.

With their new alloy, the researchers built a mechanical heat switch of prototypes. This device can automatically control the heat flow based on temperature changes. They found that the operating temperature of the alloy can be finished by adapting its composition, which means that it is adaptable for different applications. This flexibility could prove to be invaluable to develop devices for different space missions with different thermal requirements.

The simplicity and reliability of mechanical systems that use this alloy could make future space missions much reliable and at the same time reduce the complexity and weight of spatial vehicle systems. If space research extends and we venture into increasingly challenging environments, materials such as this new alloy will be of essential importance for building up the reliable equipment required for mission success.

Source: new cryogenic form memory alloy for space

Categories
Entertainment

Heavy -Metallic musician are over with 76

Legendary Heavy -Metal musician Ozzy Osbourne died at the age of 76.

Relatives: peace in peace! Bill Cosby, Tracee Ellis Ross, Eddie Griffin and other prominent pay Malcolm-Jamal Warner Tribute

The heavy metal musician Ozzy Osbourne disappears at the age of 76

According to the New York Post, the Ozzy Osbourne family published an explanation to New York Post on Tuesday, July 22nd. In addition, it was found in the explanation that Ozzy died “surrounded by love”.

“With more sadness than just convey, we have to report that our beloved Ozzy Osbourne died this morning. He was with his family together and surrounded by love. We ask everyone to respect our privacy at that time. Sharon, Jack, Kelly, Aimee and Louis,” says the explanation.

According to the Outlet, Ozzy's death arrives in January 2020 almost six years after his diagnosis with Parkinson's disease in the world. However, Fox News finds that Ozzy learned about his diagnosis in 2003. In addition, he reportedly survived from his wife Sharon and the above children.

Social media reacts alongside Elton John, Flavor Flav & More

Social media user reacted to the news from Ozzy Osbourne's Passing at 76 in the comment area of the shadow area.

Instagram user @brskash wrote, They appreciate his last concert even more Rip Ozzy. “

While Instagram user @iamluhhhayy was added, Man ForeReal WTF goes on “

Instagram user @briaag wrote, Everyone except Trump makes me angry. “

While Instagram user @Eyehhatephil was added, Backto -Back days with 2 legendary stars is a crazy work. “

Instagram user @onewaycarme wrote,Lord, I know that it comes in three, but just make sure that the next one starts with a t and ends with a P. “

While Instagram user @Bighomieblocks was added,Loved his show 🙌 rip “

Instagram user @authorjon wrote,The last 24 hours were sad “

While Instagram user @sixela.alexis_ was added,Lawd, what's going on. It's only on Tuesday “

In the meantime, Tammy Rivera wrote:

“Damned”

In addition, Flavor Flav took over to X.

Man ,,, Real Heart about the death of Ozzy Osbourne, we go far back and it was a real honor to see how he was recorded in @rockhall last year. Send my love and prayers to Sharon and his children and his whole family. Rip 🤍 pic.twitter.com/yvkpaz6fkg

– Flavor Flav (@flaPreflav) July 22, 2025

In addition, Elton John went on Instagram to add:

“To hear as sad as the news from @ozzyosbourne die. He was a dear friend and a huge Wegerlner who secured his place in the pantheon of the rock gods – a real legend. He was also one of the funniest people I've ever met.

Further details about Ozzy Osbourne & his career as a heavy -metal musician

According to Newsweek, Ozzy Osbourne as a member of the heavy metal Black Sabbath Group. Finally he was called “The Prince of Darkness” and started his own solo career in 1979. Finally, Ozzy and his family with their MTV hit show “The Osbournes” became approaches to households. According to the Outlet, Ozzy was awarded five Grammy prices in the course of his career and included in the British Music Hall of Fame and the US Rock and Roll Hall of Fame.

According to Outlet, Ozzy's death will come together with his black Sabbath bandmates in Birmingham, England just a few weeks after his farewell concert.

Relatives: Update: Further details were unveiled about the accidental drowning of Malcolm-Jamal Warner

What do you think with co -apartments?

Categories
Technology

Nice Britain has simply began its prime supercomputer. That is how it’s worldwide

Great Britain has just launched its most advanced supercomputer – the 11th most powerful in the world.

Iambard-Ai, host at the University of Bristol, officially went live this week. The machine was built by Hewlett-Packard Enterprises (HPE) using its CRAY ex-architecture and equipped with over 5400 Nvidia Grace Hopper-Superchips.

The ROW calculation performance is measured at 216.5 petaflops with a theoretical performance of 278.6 petaflops. For the uninitiated, a Petaflop corresponds to 1 billiard (1,000,000,000,000,000) calculations per second. The system is more than 10 times faster than the next snack supercomputer Great Britain and Njoerd Supercluster in London.

Financed by £ 225m ($ 300 million) in government benefit, Iambard-Ai is designed in such a way that you carry out sophisticated artificial intelligence and scientific calculations, from the modeling of protein structures to the simulation of climate change and the training of large language models.

How is Iambard-Ai comparable to the most powerful supercomputers in the world

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While Isambard-Ai has become the most powerful supercomputer in Great Britain on a global stage, it is on violent competition. After TOP500 rankingThe current world leader is El Capitan in the United States, who takes on astonishing 1,742 petaflops of actual performance.

Frontier and Aurora take second and third place, both American systems that work over the 1000 peta flop threshold-of an exaflop. The top Three are the only operational Exascale supercomputers worldwide.

Europe's leader, Germany's Jupiter Booster, occupies fourth place worldwide. The continent also houses four other machines in the top 10: Italy's HPC6 (6th), the Switzerland Alps (8th), Finlands Lumi (9th) and Italy's Leonardo (10th).

Nevertheless, Iambard-Ais Entry into the Top 11 is an important leap for the UK, its Labor government the country wants to make the country a guide in AI development.

Peter Kyle, the British science, innovation and technology secretary in Great Britain, said that the new machine would “drive” Britain in the “front of the AI discovery”.

“Today we have put the country's most powerful computer system into our hands in British researchers and entrepreneurs,” he said.

The first applications of Iambard-Ai include switching on a prostate cancer detection system developed by University College London and the support of Liverpool researchers to discover greener, more sustainable industrial materials.

But the reign of Isambard-Ais at the top can be short-lived. In June, the administration of Prime Minister Keir Starrer in Edinburgh, a supercomputer in Edinburgh 750 million GBP, was committed to giving the United Kingdom of one of the world's few Exascale systems.

Categories
Sport

Alex Anzalone is disillusioned by contract talks with lions

  • Eric WoodyardChristmas 22, 2025, 12:15 p.m.

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      Eric Woodyard covers Detroit Lions for ESPN. In September 2019, he came to the Midwest region as an NBA reporter to ESPN before switching to his current role in April 2021. The native flint, me. Is a graduate of the Western Michigan University and has also copied three books: “Wasted”, “Ethans Talent Search” and “All in: The Krvin Torbert Torbert Story”. He is a proud parent of a son, Ethan.

Alen Park, Michigan – Lions linacker Alex Anzalone wants to end his career in Detroit, but admits that he was “disappointed” how his contract negotiations went as far as this post.

Anzalone, who deals with a thigh injury, has not yet practiced, but was discovered in the Meijer Performance Center, in which he roams the sidelines on the third day of the training camp in team equipment.

“I'm disappointed, I will just say that. I'm disappointed,” said Anzalone on Tuesday about his contract negotiation.

Although the 30-year-old has expressed his wish to achieve a new contract a long time ago when he did not expect to divided any games in the regular season in the last year of his current three-year contract of $ 18.75 million, which was signed in 2023.

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However, he finds the situation strange because of his story with the Lions in the last four seasons in which he was a key piece of the team of the team for relevance.

“Sure. This is a strange situation and was not at my end or end of my agent,” said Anzalone when he spoke to reporters for the first time.

Anzalone would not go into detail about ongoing discussions, but he has the feeling that he is underpaid in relation to other line backers in the NFL. In 2024 he began in all 10 appearances, while he described the fourth most frequent duels in the team (63) seventies for the loss.

“I want to withdraw a lion. I want this opportunity,” said Anzalone, “I feel like that.”

On Sunday, Lions head coach Dan Campbell said that he had refused to believe that Anzalone was not practically a part of a “hold-in” station due to contractual problems. And there is the possibility that Anzalone may be able to return to the exercise field without a New Deal, but his intentions are clear because he wants to help Detroit win a great bowl.

“I built so much here in my time, a four -time captain and my teammates and the city and just live here,” said Anzalone. “You could list all the reasons, but it's just important to me. I have the feeling that I love this place and I want this opportunity.”

Lions All-Pro Safety Kerby Joseph is a big fan of Anzalone and his role in defense and says that he supports “whatever he believes that he has to do it is best and that's just him.”

Categories
Health

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